Science communication has changed as the tools have gotten better. But creativity has always found a way to effectively communicate even with crude tools.
Even without fancy computer graphics, very complex biological reactions could be visualized. It just took hundreds of people. From 1971. Narrated at the beginning in a tie by Paul Berg at Stanford. He won the Nobel Prize in 1980 “for his fundamental studies of the biochemistry of nucleic acids, with particular regard to recombinant-DNA.”
No animation, just hundreds of people and a fire extinguisher. But you will probably never forget the mixture of Lewis Carroll, biology and large open spaces.